Shogo Sato Ph.D.

Principle Investigator

Assistant Professor

TREC Cancer Center Scholar

the Center for Biological Clocks Research (CBCR)

Department of Biology at Texas A&M University

Ph.D., Waseda University, Japan, 2012

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Shogo completed his postdoc training with Prof. Kosaku Uyeda at the University of Texas Southwestern Medical Center at Dallas, Texas, and Prof. Paolo Sassone-Corsi at the University of California, Irvine with support from the Brain & Behavioral Research Foundation and the Della Martin Research Foundation. 

In his past career, he has accumulated a broad research background in circadian biology combined with growing knowledge and experiences in physiology, biochemistry, molecular biology, epigenetics, and metabolism. His research interest is to understand how the biological circadian system programs metabolic and epigenetic functions and to establish novel health promotion strategies to promote health and reverse metabolic diseases, cancer, and aging through metabolic and epigenetic activation of circadian clock functions.

Shogo published the research paper in Cell demonstrating how aging reprograms the circadian control of metabolic pathways in mouse liver and adult stem cells. In addition, Shogo demonstrated the time-of-day-dependent impact of exercise on metabolic activation in mouse skeletal muscle, which was published in Cell Metabolism. A follow-up study, revealing systemic metabolic coordination in response to exercise performed at different time-of-day, was published in Cell Metabolism.

The goals of his independent lab started at Texas A&M University in 2021 are 1) to achieve a fundamental understanding of the intertwined link between metabolism, epigenetics, and the circadian clock, and 2) to establish translational interventions targeting the circadian clock system to promote human health.